Comparative, adaptiveandfunctional skeletal biology

Coesel SN, Baumgartner AC, Teles LM, Ramos AA, Henriques NM, Cancela L, Varela JCS (2008) Nutrient limitation is the main regulatory factor for carotenoid accumulation and for Psy and Psd steady state transcript levels in Dunaliella salina (chlorophyta) exposed to high light and salt stress. Marine Biotechnology 10:602-611
http://dx.doi.org/10.1007/s10126-008-9100-2

Conceição N, Laizé V, Simões B, Pombinho AR, Cancela ML (2008) Retinoic acid is a negative regulator of matrix Gla protein gene expression in teleost fish Sparus aurata. Biochimica et Biophysica Acta 1779:28-39
http://dx.doi.org/10.1016/j.bbagrm.2007.11.003

Elandalloussi LM, Leite RB, Rodrigues PM, Afonso R, Cancela ML (2008) Effect of the herbicide Roundup on Perkinsus olseni in vitro proliferation and in vivo survival when infecting a permissive host, the clam Ruditapes decussatus. Bulletin of Environmental Contamination and Toxicology 80:512-515
http://dx.doi.org/10.1007/s00128-008-9412-y

Fonseca PJ, Serrão EA, Pina-Martins F, Silva P, Mira S, Quartau JA, Paulo OS, Cancela L (2008). The evolution of cicada songs contrasted with the relationships inferred from mitochondrial DNA (Insecta, Hemiptera). Bioacoustics 18:17-34
http://dx.doi.org/10.1080/09524622.2008.9753588

Leite RB, Brito AB, Cancela ML (2008) An oxygen molecular sensor, the HIF prolyl 4-hydroxylase, in the marine protist Perkinsus olseni. Protist 159:355-368
http://dx.doi.org/10.1016/j.protis.2008.03.002

Tanguy A, Bierne N, Saavedra C, Pina B, Bachère E, Kube M, Bazin E, Bonhomme F, Boudry P, Boulo V, Boutet I, Cancela L, Dossat C, Favrel P, Huvet A, Jarque S, Jollivet D, Klages S, Lapègue S, Leite R, Moal J, Moraga D, Reinhardt R, Samain JF, Zouros E, Canario A (2008) Increasing genomic information in bivalves through new EST collections in four species: Development of new genetic markers for environmental studies and genome evolution. Gene 408:27-36
http://dx.doi.org/10.1016/j.gene.2007.10.021

Tiago DM, Cancela ML, Aureliano M, Laizé V (2008) Vanadate proliferative and anti-mineralogenic effects are mediated by MAPK and PI 3K/Ras/Erk pathways in a fish chondrocyte cell line. FEBS Letters 582:1381-1385
http://dx.doi.org/10.1016/j.febslet.2008.03.025

Tiago DM, Laizé V, Cancela ML (2008) Alternatively spliced transcripts of Sparus aurata insulin-like growth factor 1 are differentially expressed in adult tissues and during early development. General and Comparative Endocrinology 157:107-115
http://dx.doi.org/10.1016/j.ygcen.2008.04.006

Tiago DM, Laizé V, Cancela ML, Aureliano M (2008) Impairment of mineralization by metavanadate and decavanadate solutions in a fish bone-derived cell line. Cell Biology and Toxicology 24:253-263
http://dx.doi.org/10.1007/s10565-007-9034-x

Viegas CSB, Simes DC, Laizé V, Williamson MK, Price PA, Cancela ML (2008) Gla-rich protein (GRP): a new vitamin K-dependent protein identified from sturgeon cartilage and highly conserved in vertebrates. Journal of Biological Chemistry 283:36655-36664
http://dx.doi.org/10.1074/jbc.M802761200

Ascenso RMT, Leite RB, Afonso R, Cancela ML (2007) Suppression-subtractive hybridization: A rapid and inexpensive detection methodology for up-regulated Perkinsus olseni genes. African Journal of Biochemical Research 1:24-28
http://academicjournals.org/article/article1380017399_Ascenso%20et%20al.pdf

Cancela ML, Laizé V (2007) Transcrição alternativa e editação do RNA: uma contribuição essencial na evolução do genoma. In: O Mundo do RNA: Novos desafios e Perspectivas Futuras, Arraiano CM, Fialho AM (Eds). LIDEL-Edições Técnicas, Lisbon. pp83-96 (ISBN: 978-972-757-419-3)

Fonseca VG, Laizé V, Valente MS, Cancela ML (2007) Identification of an osteopontin-like protein in fish associated with mineral formation. FEBS Journal 274:4428-4439
http://dx.doi.org/10.1111/j.1742-4658.2007.05972.x

Kohli V, Robles V, Cancela ML, Acker JP, Waskiewicz AJ, Elezzabi AY (2007) An alternative method for delivering exogenous material into developing zebrafish embryos. Biotechnology and Bioengineering 98:1230-1241
http://dx.doi.org/10.1002/bit.21564

Marques CL, Rafael MS, Cancela ML, Laizé V (2007) Establishment of primary cell cultures from fish calcified tissues. Cytotechnology 55:9-13
http://dx.doi.org/10.1007/s10616-007-9098-8

Pittman K, Rønnestad I, Gavaia P, Cancela ML, Guerreiro P, Ribeiro L, Aragão C, Hamre K, Moren M, Yúfera M, Conceição L (2007) Fish larval research: a tool for sustainable food production and understanding environmental impacts on developing organisms. Aquaculture Europe 32:5-10

Robles V, Barbosa V, Herráez MP, Martínez-Páramo S, Cancela ML (2007) The antifreeze protein type I (AFP I) increases seabream (Sparus aurata) embryos tolerance to low temperatures. Theriogenology 68:284-289
http://dx.doi.org/10.1016/j.theriogenology.2007.05.003

Robles V, Cancela ML (2007) Lipid-based transfection as a method for gene delivery in zebrafish (Danio rerio) embryos. Aquaculture Research 38:1317-1322
http://dx.doi.org/10.1111/j.1365-2109.2007.01806.x

Rønnestad I, Gavaia PJ, Viegas CSB, Verri T, Romano A, Nilsen TO, Jordal A-E0, Kamisaka Y, Cancela ML (2007) Oligopeptide transporter PepT1 in Atlantic cod (Gadus morhua L.): cloning, tissue expression and comparative aspects. Journal of Experimental Biology 210:3883-3896
http://dx.doi.org/10.1242/jeb.007898

Stefanni S, Porteiro FM, Bettencourt R, Gavaia PJ, Santos RS (2007) Molecular insights indicate that Pachycara thermophilum (Geistdoerfer, 1994) and P. saldanhai (Biscoito and Almeida, 2004) (Perciformes: Zoarcidae) from the Mid-Atlantic Ridge are synonymous species. Molecular Phylogenetics and Evolution 45:423-426
http://dx.doi.org/10.1016/j.ympev.2007.02.001

Tiago DM, Laizé V, Aureliano M, Cancela ML (2007) Vanadate effects on bone metabolism: Fish cell lines as an alternative to mammalian in vitro systems. In: Vanadium Biochemistry, Alves MA (Ed). Research Signpost, India. pp269-283 (ISBN: 978-81-308-0184-1)

Braga D, Laizé V, Tiago DM, Cancela ML (2006) Enhanced DNA transfer into fish bone cells using polyethylenimine. Molecular Biotechnology 34:51-54
http://dx.doi.org/10.1385/MB:34:1:51

Gavaia PJ, Simes DC, Viegas CSB, Pinto J, Ortiz-Delgado JB, Kelsh RN, Sarasquete MC, Cancela ML (2006) Osteocalcin and matrix Gla protein in zebrafish (Danio rerio) and Senegal sole (Solea senegalensis): comparative gene and protein expression during larval development through adulthood. Gene Expression Patterns 6:637-652
http://dx.doi.org/doi:10.1016/j.modgep.2005.11.010

Laizé V, Viegas CSB, Price PA, Cancela ML (2006) Identification of an osteocalcin isoform in fish with a large acidic prodomain. Journal of Biological Chemistry 281:15037-15043
http://dx.doi.org/10.1074/jbc.M600373200

Ortiz-Delgado JB, Simes DC, Viegas CSB, Schaff BJ, Sarasquete C, Cancela ML (2006) Cloning of matrix Gla protein in a marine cartilaginous fish, Prionace glauca: preferential protein accumulation in skeletal and vascular systems. Histochemistry and Cell Biology 126:89-101
http://dx.doi.org/10.1007/s00418-005-0125-6

Rafael MS, Laizé V, Cancela ML (2006) Identification of Sparus aurata bone morphogenetic protein 2: Molecular cloning, gene expression and in silico analysis of protein conserved features in vertebrates. Bone 39:1373-1381
http://dx.doi.org/10.1016/j.bone.2006.06.021

Sarrazin J, Sarradin PM, Allais AG, Almeida D, Bernagout S, Bettencourt R, Bonnivard E, Brandou V, Briand P, Bruneaux M, Buffier E, Burnet JB, Byrne N, Cardigos F, Coiras E, Cosson R, Cottin D, Cuvelier D, Dentrecolas S, Dorval P, Dupont J, Fabri MC, Gavaia P, Godfroy A, Gouillou M, Gronemann J, Hamel G, Hamon M, Higuet D, Hoge U, Jollivet D, LeGall C, Legendre P, Leroux D, Lesongeur F, Legrand J, Léon P, Lévèque JP, Martins I, Ondréas H, Riou V, Rodier P, Sauter E, Savino E, Sebastiao L, Shillito B, Siméoni P, Schultz A, Sinquin JM, Sudreau JP, Tanguy A, Taylor P, Vuillemin R, Waldmann C, Zal F (2006) MoMARETO: a cruise dedicated to the spatio-temporal dynamics and the adaptations of hydrothermal vent fauna on the Mid-Atlantic Ridge. InterRidge News 15:24-33
http://archimer.ifremer.fr/doc/2006/publication-6476.pdf

Simões B, Conceição N, Viegas CSB, Pinto JP, Gavaia PJ, Hurst LD, Kelsh RN, Cancela ML (2006) Identification of a promoter element within the zebrafish colXα1 gene responsive to Runx2 isoforms Osf2/Cbfa1 and til-1 but not to pebp2αA2. Calcified Tissue International 79:230-244
http://dx.doi.org/10.1007/s00223-006-0111-6

Cancela ML, Laizé V (2005) Replicação do DNA genómico. In: Biologia Celular e Molecular, 4a edição, Azevedo C (Ed). LIDEL-Edições Técnicas, Lisbon. pp141-152 (ISBN 978-972-757-354-1)

Conceição N, Silva AC, Fidalgo J, Belo J, Cancela ML (2005) Identification of alternative promoter usage for matrix Gla protein gene: evidence for differential expression during early development in Xenopus laevis. FEBS Journal 272:1501-1510
http://dx.doi.org/10.1111/j.1742-4658.2005.04590.x

Elandalloussi LM, Leite RB, Rodrigues PM, Afonso R, Nunes PA, Cancela ML (2005) Effect of antiprotozoal drugs on the proliferation of the bivalve parasite Perkinsus olseni. Aquaculture 243:9-17
http://dx.doi.org/10.1016/j.aquaculture.2004.09.038

Elandalloussi LM, Rodrigues PM, Afonso R, Leite RB, Nunes PA, Cancela ML (2005) Shikimate and folate pathways in the protozoan parasite, Perkinsus olseni. Molecular and Biochemical Parasitology 142:106-109
http://dx.doi.org/10.1016/j.molbiopara.2005.03.014

Elworthy S, Pettifer A, Pinto JP, Cancela ML, Kelsh RN (2005) Phox2b function in the enteric nervous system is conserved in zebrafish and is sox10-dependent. Mechanisms of Development 122:659-669
http://dx.doi.org/10.1016/j.mod.2004.12.008

Engrola S, Conceição LEC, Gavaia PJ, Cancela ML, Dinis MT (2005) Effects of pre-weaning feeding regime on growth, survival, and deformation of Senegalese sole, Solea senegalensis (Kaup, 1858). Israeli Journal of Aquaculture 57:10-18
https://evols.library.manoa.hawaii.edu/bitstream/handle/10524/19125/57_1_Engrola.pdf

Fonseca VG, Lago-Lestón A, Laizé V, Cancela ML (2005) Rapid identification of differentially expressed genes by in situ screening of bacteria. Molecular Biotechnology 30:163-165
http://dx.doi.org/10.1385/MB:30:2:163

Frazão C, Simes DC, Coelho R, Alves D, Williamson MK, Price PA, Cancela ML, Carrondo MA (2005) Structural evidence of a fourth Gla residue in fish osteocalcin: biological implications. Biochemistry 44:1234-1242
http://dx.doi.org/10.1021/bi048336z

Laizé V, Martel P, Viegas CSB, Price PA, Cancela ML (2005) Evolution of matrix and bone γ-carboxyglutamic acid proteins in vertebrates. Journal of Biological Chemistry 280:26659-26668
http://dx.doi.org/10.1074/jbc.M500257200

Laizé V, Pombinho AR, Cancela ML (2005) Characterization of Sparus aurata osteonectin cDNA and in silico analysis of protein conserved features: Evidence for more than one osteonectin in Salmonidae. Biochimie 87:411-420
http://dx.doi.org/10.1016/j.biochi.2005.01.008

Mira S, Wolff K, Cancela ML (2005) Isolation and characterization of microsatellites markers in Bonelli’s eagle (Hieraaetus fasciatus). Molecular Ecology Notes 5:493-495
http://dx.doi.org/10.1111/j.1471-8286.2005.00967.x

Ortiz-Delgado JB, Simes DC, Gavaia PJ, Sarasquete C, Cancela ML (2005) Osteocalcin and matrix Gla protein in developing teleost teeth: identification of sites of mRNA and protein accumulation at single cell resolution. Histochemistry and Cell Biology 124:123-130
http://dx.doi.org/10.1007/s00418-005-0015-y

Pinto JP, Conceição NM, Viegas CSB, Leite RB, Hurst LD, Kelsh RN, Cancela ML (2005) Identification of a new pebp2αA2 isoform from zebrafish runx2 capable of inducing osteocalcin gene expression in vitro. Journal of Bone and Mineral Research 20:1440-1453
http://dx.doi.org/10.1359/JBMR.050318

Elandalloussi LM, Leite RB, Afonso R, Nunes PA, Robledo JAF, Vasta GR, Cancela ML (2004) Development of a PCR-ELISA assay for diagnosis of Perkinsus marinus and Perkinsus atlanticus infections in bivalve molluscs. Molecular and Cellular Probes 18:89-96
http://dx.doi.org/10.1016/j.mcp.2003.09.008

Leite RB, Afonso R, Cancela ML (2004) Perkinsus sp. infestation in carpet-shell clams, Ruditapes decussatus (L), along the Portuguese coast. Results from a 2-year survey. Aquaculture 240:39-53
http://dx.doi.org/10.1016/j.aquaculture.2004.05.014

Pombinho AR, Laizé V, Molha DM, Marques SMP, Cancela ML (2004) Development of two bone-derived cell lines from the teleost Sparus aurata; evidence for extracellular matrix mineralization and cell-type specific expression of matrix Gla protein and osteocalcin. Cell and Tissue Research 315:393-406
http://dx.doi.org/10.1007/s00441-003-0830-1

Simes DC, Williamson MK, Schaff BJ, Gavaia PJ, Ingleton PM, Price PA, Cancela ML (2004) Characterization of osteocalcin (BGP) and Matrix Gla Protein (MGP) fish specific antibodies: validation for immunodetection studies in lower vertebrates. Calcified Tissue International 74:170-180
http://dx.doi.org/10.1007/s00223-003-0079-4

Streiff R, Mira S, Castro M, Cancela ML (2004) Multiple paternity in Norway lobster (Nephrops norvegicus L.) assessed with microsatellite markers. Marine Biotechnology 6:60-66
http://dx.doi.org/10.1007/s10126-003-0015-7

Aurelle D, Guillemaud T, Afonso P, Morato T, Wirtz P, Santos RS, Cancela ML (2003) Genetic study of Coris julis (Osteichtyes, Perciformes, Labridae) evolutionary history and dispersal abilities. C. R. Biologies 326:771-785
http://dx.doi.org/10.1016/j.crvi.2003.08.001

Elandalloussi LM, Afonso R, Nunes PA, Cancela ML (2003) Effect of desferrioxamine and 2,2’-bipyridyl on the proliferation of Perkinsus atlanticus. Biomolecular Engineering 20:349-54
http://dx.doi.org/10.1016/S1389-0344(03)00047-9

Leite RM, Rodrigues PM, Elandalloussi LM, Afonso RM, Nunes PA, Cancela ML (2003) Perkinsus atlanticus – Desenvolvimento de um método de diagnóstico para detecção da infecção em moluscos bivalves. Boletim de Biotecnologia 75:8-10
http://www.spbt.pt/getfile.aspx?tipo=pub&fileid=5

Pinto JP, Conceição N, Gavaia PJ, Cancela ML (2003) Matrix Gla protein gene expression and protein accumulation co-localize with cartilage distribution during development of the teleost fish Sparus aurata. Bone 32:201-210
http://dx.doi.org/10.1016/S8756-3282(02)00981-X

Simes DC, Williamson MK, Ortiz-Delgado JB, Viegas CSB, Price PA, Cancela ML (2003) Purification of matrix Gla protein (MGP) from a marine teleost fish, Argyrosomus regius: calcified cartilage and not bone as the primary site of MGP accumulation in fish. Journal of Bone and Mineral Research 18:244-259
http://dx.doi.org/10.1359/jbmr.2003.18.2.244

Conceição N, Henriques NM, Ohresser MCP, Hublitz P, Schüle R, Cancela ML (2002) Molecular cloning of the Matrix Gla Protein gene from Xenopus laevis: functional analysis of the promoter identifies a calcium sensitive region required for basal activity. European Journal of Biochemistry 269:1947-1956
http://dx.doi.org/10.1046/j.1432-1033.2002.02846.x

Gavaia PJ, Dinis MT, Cancela ML (2002) Osteological development and abnormalities of the vertebral column and caudal skeleton in larval and juvenile stages of hatchery-reared Senegal sole (Solea senegalensis). Aquaculture 211:305-323
http://dx.doi.org/10.1016/S0044-8486(02)00167-9

Henriques M, Lourenço R, Almada F, Calado G, Gonçalves D, Guillemaud T, Cancela ML, Almada VC (2002) A revision of the status of Lepadogaster lepadogaster (Teleostei: Gobiesocidae): Sympatric subspecies or a long misunderstood blend of species? Biological Journal of the Linnean Society 76:327-338
http://dx.doi.org/10.1046/j.1095-8312.2002.00067.x

Mira S, Billot C, Guillemaud T, Palma L, Cancela ML (2002) Isolation and characterization of polymorphic microsatellite markers in Eurasian Vulture Gyps fulvus. Molecular Ecology Notes 2:557-558
http://dx.doi.org/10.1046/j.1471-8286.2002.00314.x

Robledo JAF, Nunes PA, Cancela ML, Vasta GR (2002) Development of an in vitro clonal culture and characterization of the rRNA gene cluster of Perkinsus atlanticus, a protistan parasite of the clam Tapes decussatus. Journal of Eukaryotic Microbiology 49:414-422
http://dx.doi.org/10.1111/j.1550-7408.2002.tb00221.x

Viegas CSB, Pinto JP, Conceição N, Simes DC, Cancela ML (2002) Cloning and characterization of the cDNA and gene encoding Xenopus laevis osteocalcin. Gene 289:97-107
http://dx.doi.org/10.1016/S0378-1119(02)00480-8

Cancela ML, Ohresser MCP, Reia JP, Viegas CSB, Williamson MK, Price PA (2001) Matrix Gla protein in Xenopus laevis: molecular cloning, tissue distribution and evolutionary considerations. Journal of Bone and Mineral Research 16:1611-1622
http://dx.doi.org/10.1359/jbmr.2001.16.9.1611

Palma L, Mira S, Cardia P, Beja P, Guillemaud T, Ferrand N, Cancela ML, Cancela da Fonseca L (2001) Sexing Bonelli´s eagle nestlings: Morphometrics versus molecular techniques. Journal of Raptor Research 35:187-193
https://sora.unm.edu/sites/default/files/journals/jrr/v035n03/p00187-p00193.pdf

Pearson G, Serrão EA, Cancela ML (2001) Suppression subtractive hybridization for studying gene expression during aerial exposure and desiccation in fucoid algae. European Journal of Phycology 36:359-366
http://dx.doi.org/10.1017/S0967026201003377

Pinto JP, Ohresser MCP, Cancela ML (2001) Cloning of the bone Gla protein gene from the teleost fish Sparus aurata. Evidence for overall conservation in gene organization and bone-specific expression from fish to man. Gene 270:77-91
http://dx.doi.org/10.1016/S0378-1119(01)00426-7

Streiff R, Guillemaud T, Alberto F, Magalhães J, Castro M, Cancela ML (2001) Isolation and characterization of microsatellite loci in the Norway lobster (Nephrops norvegicus). Molecular Ecology Notes 1:71-72
http://dx.doi.org/10.1046/j.1471-8278.2001.00029.x

Carvalho MC, Streiff R, Guillemaud T, Afonso P, Santos RS, Cancela ML (2000) Isolation and characterization of polymorphic microsatellite markers in Abudefduf luridus (Pisces: Pomacentridae). Molecular Ecology Notes 9:993-994
http://dx.doi.org/10.1046/j.1365-294x.2000.00939.x

Gavaia PJ, Sarasquete C, Cancela ML (2000) Detection of mineralized structures in very early stages of development of marine Teleostei using a modified alcian blue-alizarin red double staining technique for bone and cartilage. Biotechnic & Histochemistry 75:79-84
http://dx.doi.org/10.3109/10520290009064151

Guillemaud T, Almada F, Serrão Santos R, Cancela ML (2000) Interspecific utility of microsatellites in fish: a case study of (CT)n and (GT)n markers in the shanny Lipophrys pholis (Pisces: Blenniidae) and their use in other Blennioidei. Marine Biotechnology 2:248-253
http://dx.doi.org/10.1007/s101269900029

Guillemaud T, Cancela ML, Afonso P, Morato T, Santos RS, Wirtz P (2000) Molecular insights in the taxonomic status of Coris atlantica (Pisces: Labridae). Journal of the Marine Biological Association of the UK 80:929-933
http://journals.cambridge.org/article_S0025315400002915

Guillemaud T, Streiff R, Serrão Santos R, Afonso P, Morato T, Cancela ML (2000) Microsatellite characterization in the rainbow wrasse Coris julis (Pisces: Labridae). Molecular Ecology Notes 9:631-632
http://dx.doi.org/10.1046/j.1365-294x.2000.00882-1.x

Cancela ML, Hu B, Price PA (1997) Effect of cell density and growth factors on Matrix Gla protein expression by normal rat kidney cells. Journal of Cellular Physiology 171:125-134

Kirfel J, Kelter M, Cancela ML, Price PA, Schüle R (1997) Identification of a novel negative retinoic acid responsive element in the promoter of the human matrix Gla protein gene. Proceedings of the National Academy of Sciences of the United States of America 94:2227-2232

Cancela ML, Williamson MK, Price PA (1995) Amino acid sequence of Bone Gla protein from the African clawed toad Xenopus laevis and the fish Sparus aurata. International Journal of Peptide and Protein Research 46:419-423

Cancela ML, Williamson MK, Price PA (1994) The putative RGD-dependent cell adhesion activity of matrix Gla protein is due to higher molecular weight contaminants. Journal of Biological Chemistry 269:12185-12189

Cancela ML, Williamson MK, Price PA (1993) Retinoic acid increases matrix Gla protein in rat plasma. Nutrition Research 13:87-91

Rannels SR, Cancela ML, Wolpert EB, Price PA (1993) Matrix Gla protein mRNA expression in cultured type II pneumocytes. American Journal of Physiology 265:L270-L278

Cancela L, Ishida H, Bishop JE, Norman AW (1992) Local chromatin changes accompany the expression of the calbindin D28k gene: tissue-specificity and effect of vitamin D activation. Molecular Endocrinology 6:468-475

Cancela ML, Price PA (1992) Retinoic acid induces matrix Gla protein gene expression in human cells. Endocrinology 130:102-108

Cancela L, Hsieh CL, Francke U, Price PA (1990) Molecular structure, chromosome assignment, and promoter organization of the human matrix Gla protein gene. Journal of Biological Chemistry 265:15040-15048

Cancela L, Nemere I, Norman AW (1988) 1α,25(OH)2 vitamin D3: A steroid hormone capable of producing pleiotropic receptor-mediated biological responses by both genomic and non-genomic mechanisms. Journal of Steroid Biochemistry 30:33-39

Cancela L, Theofan G, Norman AW (1988) The pleiotropic vitamin D hormone. In: New Comprehensive Biochemistry. Hormones and their actions, Part I, Cooke BA, King RJB, Van der Molen HJ (Eds) Elsevier Science Publishers, pp 269-289

De Vernejoul MC, Benamout MP, Cancela L, Miravet L, Kuntz D, Gueris J, Gardin JP (1988) Primary hyperparathyroidism seen in rheumathology. Clinical symptoms and the relation between bone histologic signs and biological parameters. Revue du Rhumatisme et des Maladies Osteo-Articulaires 55:489-494

Minghetti PP, Cancela L, Fujisawa Y, Theofan G, Norman AW (1988) Molecular structure of the chicken vitamin D-induced calbindin-D28k gene reveals eleven exons, six Ca2+ binding domains and numerous promoter regulatory elements. Molecular Endocrinology 2:355-367

Minghetti PP, Cancela L, Ishida H, Norman AW (1988) 1,25-dihydroxyvitamin D3, its receptor and the eukaryotic genome. In: Vitamin D: molecular, cellular and clinical endocrinology, Norman AW, Schaffer K, Grigoleit HG, Von Herrath D (Eds) Walter de Gruyter, Berlin, pp 479-488

Parisi M, Cancela L (1988) Time course studies on phosphate transfer in frog urinary bladder. Kidney International 33:58-63

Rebut-Bonneton C, Ly SY, Cancela L (1988) Calcium-transport in quiescent and 1,25-dihydroxycholecalciferol-stimulated human osteosarcoma cells. Role in 24 hydroxylase enhancement. Hormone and Metabolic Research 20:339-343

Cancela L, Marie PJ, Le Boulch N, Miravet L (1987) Lack of biological activity of vitamin D3-3β-sulfate during lactation in vitamin D-deficient rats. Reproduction Nutrition Development 27:979-997

Cancela L, Nemere I, Theofan G, Leathers V, Reichel H, Belk E, Fujisawa Y, Ishida H, Bishop JE, Jones G, Minghetti PP, Norman AW (1987) The vitamin D endocrine system: pleiotropic interactions which contribute to calcium homeostasis. In: Calcium binding proteins in health and disease. Norman AW, Vanaman TC, Means A (Eds) Academic Press, New York, pp. 13-22

Cancela L, Rebut-Bonneton C (1987) Regulation of 24-hydroxylase activity in mouse skin fibroblasts by cholecalciferol derivatives, triamcinolone acetonide and a calcium modulating agent, nicardipine. Journal of Steroid Biochemistry 28:479-484

Theofan G, Minghetti PP, Cancela L, Fujisawa Y, N’Gwyen A, Norman AW (1987) Calbindin D (the vitamin D-induced calcium binding protein): Regulation of gene expression by 1,25(OH)2D3. In: Calcium regulation and bone metabolism: Basic and clinical aspects, Vol. 9. Cohn DV, Martin TJ, Meunier PJ (Eds) Excerpta Medica, Amsterdam, pp. 808-810

Cancela L, Le Boulch N, Miravet L (1986) Relationship between the vitamin D content of maternal milk and the vitamin D status of nursing women and paired breast-fed infants. Journal of Endocrinology 110:43-50

Le Boulch N, Cancela L, Miravet L, Lange C (1986) Assessment of vitamin D sulfate in human milk using desorption chemical ionization mass spectrometry. Biomedical & Environmental Mass Spectrometry 13:53-56

Marie PJ, Cancela L, Le Boulch N, Miravet L (1986) Bone changes due to pregnancy and lactation: Influence of vitamin D status. American Journal of Physiology 251:E400-E406

Cancela L, Marie PJ, Le Boulch N, Miravet L (1985) Vitamin D3-3β-sulfate has less biological activity than free vitamin D3 during pregnancy in rats. Biology of the Neonate 48:274-284

Cancela L, Marie PJ, Le Boulch N, Miravet L (1985) Influence of vitamin D on mineral metabolism, hormonal status and bone histology in lactating rats and their pups. Journal of Endocrinology 105:303-309

Rebut-Bonneton C, Demignon J, Cancela L, Miravet L (1985) Effect of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 maternal loads on the maternal and fetal vitamin D metabolite levels in the rat. Reproduction Nutrition Development 25:583-590

Cancela L, Le Boulch N, Miravet L (1984) Action of vitamin D3-3β-sulfate during lactation in the rat. World Review of Nutrition and Dietetics 43:153-157

De Vernejoul MC, Girot J, Gueris J, Cancela L, Bang S, Bielakoff J, Mauntalen C, Goldberg G, Miravet L (1982) Calcium phosphate metabolism and bone disease in patients with homozygous thalassemia. Journal of Clinical Endocrinology & Metabolism 54:276-281

Le Boulch N, Cancela L, Miravet L (1982) Cholecalciferol sulfate identification in human milk by HPLC. Steroids 39:391-398

Lemaire V, Cancela L, Durepaire H, La Forest S, Miravet L, Ryckewaert A (1982) Hypercalcémie isolée révélatrice d’une sarcoidose. Un cas avec élévation du 1,25-dihydroxycholecalciferol. La Nouvelle Presse Medicale 11:1143-1144